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Muscular Dystrophy - Cavalier King Charles Spaniel Type

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Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

Dystrophin

Variant Detected:

G>T on chromosome X

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal X-Linked

Research Citation(s):

Kornegay, J. N., Bogan, J. R., Bogan, D. J., Childers, M. K., & Grange, R. W. (2011). Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements. Methods in Molecular Biology (Clifton, N.J.), 709, 105–123.

Associated Breed(s):

Cavalier King Charles Spaniel, Mixed breed,

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